Angiotensin II activates intermediate-conductance Ca2+-activated K+ channels in arterial smooth muscle cells
Y Hayabuchi, Y Nakaya, S Yasui, K Mawatari… - Journal of molecular and …, 2006 - Elsevier
Angiostensin II (Ang II) regulates the migration and proliferation of vascular smooth muscle
cells. Recent studies indicate that intermediate-conductance Ca2+-activated K+ (IKca)
channels have an important role in cell migration and proliferation. It is not known, however,
whether the action of Ang II is linked to IKca channel regulation. Here, we investigated the
modulation of IKca channels by Ang II in artery smooth muscle cells. Functional IKca
channel expression in cultured embryonic rat aorta smooth muscle (A10) cells was studied …
cells. Recent studies indicate that intermediate-conductance Ca2+-activated K+ (IKca)
channels have an important role in cell migration and proliferation. It is not known, however,
whether the action of Ang II is linked to IKca channel regulation. Here, we investigated the
modulation of IKca channels by Ang II in artery smooth muscle cells. Functional IKca
channel expression in cultured embryonic rat aorta smooth muscle (A10) cells was studied …
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